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Traumatic Brain Injury And Cell Therapy

Treating Traumatic Brain Injury


Annually, Traumatic Brain Injury (TBI) contributes to a significant number of deaths in just the United States.

TBI mainly results from an intense jolt or blow to the body or head. If an object such as a shattered skull or bullet penetrates the brain tissue, chances are high that the individual will suffer from brain injury.

The intensity of a TBI ranges from mild to severe. To have the actual figures relating to the seriousness of TBI effects is critical. The information garnered, and statistics would go a long way, as public health institutions would have the best approach on how to prevent this major problem.

Related Article – Cell Therapy: Ray Of Hope For Brain Injury
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TBI Worldwide Incidence

Traumatic brain injury makes up for about thirty percent of all the injury-related deaths in USA. This percentage is even higher in other regions across the world such as Latin America and Sub-Saharan Africa.

Villa Medica - Traumatic Brain Injury (TBI) - Statistics Infographic

Traumatic Brain Injury (TBI) – Statistics: Annualy, an estimated 10 Million people suffer a TBI event worldwide. In the European Union the yearly aggregate incidence of TBI Hospitalizations and fatalities is estimated at 235 per 100,000

Annual incidents of traumatic brain injury is approximately 180 – 250 per a hundred thousand people in the United States.

In France, this estimation is 281 per a hundred thousand people. This same estimation is 361, 322 and 430 per a hundred thousand people in South Africa, Australia and England respectively.

Research shows that over ten million people are suffering from TBI incidents every other year across the world. This number is likely to go up over the next three years.

Projections to the year 2020 indicate that traumatic brain injury will consist the third largest number of disease burden by that year.


TBI Facts And Figures

In the USA alone, up to 1.7 million people suffer brain injury yearly with deaths as high as 52,000. In hospitals, the number of those admitted goes to 275,000, while those who are treated and released are around 1.365 million, an estimation of around 80%.

Below are some additional facts about TBI:

• Medical cost for treating persons suffering from TBI comes to a close estimate of $60,000.
• In the United States, it is the cause of deaths ranging from 30.5% yearly.
• Annually, all the TBI related problems occur from mild traumatic brain injury or concussions.


Treatment options For Traumatic Brain Injury

Treatment options for TBI include medication, rest, therapies and surgery.

A surgical procedure, known as decompressive craniectomy, is carried out where parts of the skull are surgically removed so that the injured brain can swell without undergoing pressure.

Other options include therapies such as rehabilitation, cognitive behavioural therapy, occupational therapy, anger management therapy among others.


Could Cell Therapy Help Traumatic Brain Injury?

Brain injury might result in brain cells being dormant and often also lead to death of cells.
As a result, cell therapy is a viable option for treatment of traumatic brain injury as the process often leads to regeneration of new cells in the injured part.

Villa Medica - Cell Therapy Explained - Infographic

Cell Therapy is an old treatment modality which involves implantation of living cells for treatment of diseases.

These new cells integrate themselves into the injured brain tissue thus aiding in growth of new brain cells and repairing the damage.

Head injury patients who have undergone cell therapy realise various forms of improvement.

Such improvements include :
• improved motor function
• cognition and memory improvement
• improved coordination
• improvement in speech and swallowing

Medical doctors are breaking all barriers to come up with the best method to treat traumatic brain injury.

Due to inflammation of the brain resulting from a strong external force and concussion, a better approach is necessary to ascertain the brain functions normally again.

After the extraction of cells, researchers believe that exposure of damaged tissue has a significant impact on the proliferation of muscle tissue.

As much as there are still ongoing clinical trials, there is a postulation that muscle regeneration can be enhanced in people who have suffered a traumatic brain injury.


What Is Traumatic Brain Injury?

Traumatic brain injury (TBI) is sometimes referred to as intracranial injury, that occurs when the brain is injured because of an external force.

Villa Medica - Traumatic Brain Injury (TBI) - Fact Sheet Infographic

Traumatic Brain Injury (TBI) – Facts : Also known as intracranial injury, it occures when an external force injures the brain. TBI can be classidied based on severity, mechanism (closed or penetrating head injury), or other features (e.g., occurring in a specific location or over a widespread area).

The condition is usually characterized depending on mechanism-closed or penetrating head injury-severity, or other causes such as the location where it happened.

In some circumstances, TBI can lead to social, cognitive, emotional, behavioural, and physical symptoms.


Traumatic Brain Injury Symptoms

Traumatic brain injury is known to have different symptoms, which include both psychological and physical effects. The longevity of the signs varies as some may appear immediately while others take a longer time.

Signs and symptoms of mild traumatic brain injury include:

  • Headaches
  • Fatigue or drowsiness
  • Loss of balance
  • Extreme sensitivity to sound or light
  • Sensory problems like difficulty with smelling and blurred vision.

The symptoms are similar from children to adults and will vary differently in each individual. TBI is risky in males of any age group, young adults especially those between the age of 15 to 24 years, adults who are over 60 years, and newborns children up to the age of four years.


TBI Symptoms Observed in Children

Infants and young children might not be in a position to communicate their symptoms.

However, observing a child with traumatic brain injury, one may notice the following: seizures, drowsiness, depressed mood, change in sleep habits, change in feeding habits, unusual irritability and even loss of interest in favourite toys or activities.



To sum up, a traumatic brain injury is complicated by a wide range of symptoms that may lead to permanent or temporary disability;
however, with cell therapy, there’s hope for effective treatment and a productive quality of life.

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Further Reading – Quality Articles From Third Party Websites

    1. [1] NCBI – National Centre for Biotechnology Information
    2. [2] WHO – World Health Organization
    3. [3] CDC – Centres for Disease Control and Prevention
    4. [4] Hoffer et al. Journal of Biomedical Science (2017)


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