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Peripheral Artery Disease – Innovative Treatment With Cell Therapy

Cell Therapy For Peripheral Artery Disease

Peripheral Artery Disease - Innovative Treatment With Cell Therapy

Peripheral Artery Disease – Normal Artery Vs. Atherosclerotic Artery


Peripheral Artery Disease (PAD) is a progressive disease where lack of enough blood flow leads to narrowing and spasm of blood vessels outside the brain and heart.

PAD usually occurs in the veins and arteries translating to fatigue and pain often in the feet and legs.

The condition worsens when indulging in physical exercises and improves with rest.

Could Cell Therapy Help With Peripheral Artery Disease?

A standard case for the treatment of this chronic disease is endovascular revascularization or surgery.

Due to unfavorable vascular involvement or high operative risk, around 30% of patients are not candidates for this intervention.

As a result, new strategies are vital in providing these patients with a viable treatment.

Villa Medica - 3 Steps Of Cell Therapy: Protect, Repair & Regenerate

3 Steps Of Cell Therapy: Protect existing cells, Repair damaged cells and tissues & Regenerate – to promote and stimulate cell regeneration process

Cell Therapy has been identified as the best therapeutic option to administer angiogenesis. This discovery has made clinical researchers find the feasibility of new cells in individuals with coronary and peripheral artery diseases.

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels. In precise usage this is distinct from vasculogenesis, which is the “de novo formation” of endothelial cells from mesoderm cell precursors, and from neovascularization.

The results were surprising as it showed an improvement in oxygen pressure and ankle-brachial index (ABI). There was a significant reduction in chances of amputation and pain was also reduced.

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Peripheral Artery Disease Symptoms

Most individuals who have been affected by PAD usually start by experiencing discomforts like cramping and fatigue in the feet or calf area.

Villa Medica - Peripheral Artery Disease (PAD) Facts - Infographic

Peripheral Artery Disease (PAD) Facts : PAD occurs when arteries in the leg become narrowed or clogged, causing legs blood flow. 40% of people with PAD don’t have leg pain.

The condition gets worse with any physical activity due to lack of enough blood flowing to the lower body area.
While some patients experience mild to no symptoms, others experience pain while resting and non-healing wounds, skin temperature changes and pulse changes.

So far, the most common symptom of PAD is claudicationa lower limb muscle pain that is usually experienced when walking for long distances or in fast motion)

Appropriate diagnosis is vital if you suspect you may be suffering from peripheral artery disease.

Risk Factors

There are numerous factors associated with peripheral artery disease, and they include:

Poor life style choices can also be a contributing factor for PAD, and they include drug use, smoking, poor eating habits, and not engaging in enough physical exercises.

What Causes PAD ?

The known cause of PAD is mostly thromboangiitis obliterans (TAO) and atherosclerosis obliterans (ASO).

Sometimes vessels which supply blood to the kidneys, stomach, and arms are also affected, leading to blood flow issues.

Since fatty build-up occurs in all the arteries in the human body, patients are likely to suffer a heart attack.

Peripheral artery disease is a highly prevalent condition with severe mortality and morbidity.


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Further Reading – Quality Articles From Third Party Websites

    1. [1] PVD And Me
    2. [2] American College Of Cardiology
    3. [3] Healthline
    4. [4] HealthGrove
    5. [5] CardioSmart
    6. [6] ScienceDirect