Live Cell Therapy Explained: Hope For Untreatable Medical Disorders
Hope For Untreatable Medical Disorders
The medical field, especially regenerative medicine and Live Cell Therapy, is always going to be confronted with diseases that are untreatable at the current point in time. Hence, medical research is a never-ending endeavor.
Reports of success and inspiration to seek cures spur researchers to labor on incessantly. Seeing his patient recover from a serious disease with a poor prognosis engenders a sense of satisfaction and pleasure in a doctor, which is not forgotten throughout his life. But doctors are human.
A doctor proposes a promising line of treatment, but in reality, God disposes.
I do not cure disease. I just help the body heal itself. – Albert Schwitzer
Physicians cannot cure every disease, but comforting the sick and their loved ones is very much a part of healing. We should refrain from reinforcing the sense of helplessness and, instead, strive to help them look for solutions – even those out of mainstream medicine if conventional medicine cannot offer anything at that point in time. We can help make a choice as to the modality of treatment that is safe and worth trying.
The conventional medicine that we use is effective for acute emergencies, infections, traumatic injuries, acute illnesses, acute organ failure, poisoning, and treatment of many congenital abnormalities.
The best of conventional medicine must be covered. But it cannot stimulate or regenerate dysfunctional or dying organs. This is the dimension of regenerative medicine. This is the value of Live Cell Therapy. Live Cell Therapy is recognized as the most effective harmonizer of the endocrine system. It can correct immune defects.
Having seen the positive effects on many patients suffering from Multiple Sclerosis, Autism Spectrum Disorders, Cerebral Palsy and even in Liver Diseases or Cardiovascular Diseases and having seen significant responses in high percentage of Down Syndrome patients, skepticism of this treatment has been much removed many years ago.
But one cannot be certain whether live cell therapy will always work in conditions that are untreatable in conventional medicine.
What Is Cell Therapy ?
Cell Therapy belongs to the oldest forms of medical treatment and includes the following:
- Blood transfusions
- Bone marrow transplantation
- Transplantation of platelets, erythrocyte concentrates, leukocytes
- Implantation of thymus
- Transplantation of fetal cells (liver, spleen, bone marrow, pancreatic cells, etc.)
Over more than eight years, the concept of cell therapy has been identified more with the use of fetal tissue.
Cell Therapy Explained
We can define the methods as follows:
Cell Therapy is an implantation by injection of fetal or juvenile suspensions of cells or tissues in physiological solution for therapeutic purposes. The term includes implantation using live cells, lyophilized (freeze-dried) cells, frozen cells and fetal precursor stem cells prepared by primary tissue culture.
In mainstream journals and across various websites, the term Stem Cell Transplantation will be used more often and not Cell Transplantation or Cell Therapy. You will often find both these terms being used.
The term Stem Cell Transplantation (SCT) is defined as:
“Stem Cell Transplantation is a surgical procedure in which stem cells containing live tissue fragments of different organs and tissues, of human or animal origin, from fetal, neonatal, juvenile, or adult stage, are implanted to treat diseases of humans and animals.”
You will hear or read about the following terms:
Xenotransplantation, which refers to the transplantation of cells, tissue, or organs between species – i.e., from animal to man, from man to animal, or from one animal species to another, such as from goat to sheep or rabbit to monkey, etc.
Allotransplantation, which refers to the transplantation within the same species – e.g., from one man to another, from one rabbit to another, etc.
Autotransplantation, which refers to the transplantation from one part of the body to another part of the same person – for example, to take an adrenal medulla of a patient and transplant it to the corpus striatum in the brain to treat Parkinson’s disease, or to take a piece of skin from the abdomen and transplant it to a burnt area of the same patient.
Here, at Villa Medica, and on this website we are discussing stem cell transplantation (cell therapy), specifically fetal precursor stem cell transplantation and not organ transplantation. Organ transplantation is more complex technically and has a different standard of operating procedure altogether.
Some Basic Information Regarding Cell Therapy
Allotransplantation, which uses umbilical-cord blood stem cell transplantation and human embryonic stem cell transplantation, is still difficult to statistically evaluate because of the small numbers. It must be appreciated that out of more than five million patients treated by stem cells transplantation over the last seventy years, over 99% had been treated by xenotransplantation.
These xenotransplants are, in fact, much safer then even human stem cells as it is impossible to have human subjected to such stringent regulations. We have been using fetal precursor stem cell xenotransplants (FPSCXT) prepared by primary tissue culture for treatment of diseases that are presently untreatable or no longer treatable in conventional medicine.
Stem Cells can be implanted by injections (minor surgery) by administering through the following ways:
Stem cells can also be implanted by major surgery -e.g., by neurotransplantation, orthopedic reconstructive surgery, or by surface application of stem cells, such as for treatment of deep burns requiring skin grafting.
Cell Therapy – The Mechanism Explained
Patients receiving “cell extracts” or “ultrafiltrates” of different organs and tissues by injections are not getting cell transplantation or cell therapy. The therapeutic benefits of implantation of live stem cells are far superior.
Dr. Niehans himself wrote in his book that the therapeutic effects of cell therapy seem to be bound up with the cell as a unit. Research in cell biology has established the importance of the cell membrane a the ‘brain’ of the cell.
The revitalizing / regenerative effects seen following live cell therapy are most likely due to the cell signaling factors and molecules in the fetal precursor stem cell xenotransplants acting of the corresponding cell membranes of the recipient thereby regulating and reprogramming cell functions at an epigenetic level. Ultrafiltrates, which contain contain peptides, are ‘biological building blocks’ that serve at molecular level primarily as substitutes and secondarily to facilitate regeneration and repair processes where needed.
Live Cell Therapy – Stating The Facts
Cell Therapy started empirically with great success. Of course desirable effects may not have been felt in some patients. Nevertheless is is a safe form of biotherapy. There are many published medical reports on hundreds of patients showing that there are only minimal changes in the immunological laboratory parameters before and after cell therapy.
The following facts that have been known for decades have either been forgotten or ignored:
- Cell therapists have known that embryonic cells are not to be used in cell therapy because of their oncogenicity.
- Cell therapists have been using fetal precursor (or progenitor) cells from animal origin that are many generations older and no longer pluripotential. Thus, the moral and religious issues attached to the use of human embryonic cells are also avoided.
- Modern stem cell transplantation uses discrete cells, while classical stem cell transplantation (cell therapy) uses cell fragments or clusters. Immunosuppression is unnecessary and is not the protocol of live cell therapy. The advantage is that there are no drugs used that will counteract live cell therapy and reduce its effectiveness.
- There have been many published reports of success on hundreds of thousands of case reports of patients treated with cell therapy. Because this therapy is not in the university’s medical curriculum, most conventionally trained doctors are not familiar with it. Being an individualized form of biological therapy that affects the entire body, and also it is a surgical procedure, it is quite impossible to do an objective double-blind, placebo-controlled study.
- Cell Therapy has been used in Russia, Germany, and China over the last eighty years. It has been officialized as a form of medical treatment in Switzerland in 1931. It is permitted by law in Germany, with the tacit acceptance in Switzerland and Austria, endorsed indirectly by the parliament of the European Union. From the regulatory viewpoint, cell transplants are outside of regulatory controls of the State because they are neither drugs nor ‘therapeutica’, but another form of medication, individually prepared by a physician, for his specific patient, by agreement with his patient, confirmed by the signed informed consent prescribed by law. These cell transplants are prepared for one-time use only, with no shelf life, to be implanted at the time and date set by the physician. These preparations are therefore not distributed through usual channels (i.e., through pharmacies). Currently, cell therapy is not permitted legally in the USA, except under strictly controlled experimental circumstances.
Related Article – Cell Therapy Facts: What Is Cell Therapy?
> Read the full article here
Breakthrough Knowledge Through Practice & Research
At Villa Medica, all patients are receiving fetal precursor stem cells xenotransplants prepared by primary tissue cultures for treatment. These cells are from foetuses reared in accredited closed colonies. These animals are bred in adherence to the regulations of the American Association for Accreditation of Laboratory Animal Care (AAALAC) and the Food and Drug Administration (FDA), USA.
Live Cell Therapy has been utilized by brilliant and dedicated doctors -mainly in Europe (especially in Germany and Russia) -for over one hundred years to treat patients who have failed treatment with conventional medicine at any time. This modality has not been without its critics among colleagues in allopathic medicine.
PRIMUM NON NOCERE – first, do no harm.
Many notable doctors -including Nobel Prize laureates- have helped to advance the knowledge through their practice and research in this field, for which we should be eternally greatful. This modality of treatment must be used with attention to detail and fine-tuned in the light of up-to-date scientific knowledge.
As doctors, we are we should be always reminded to abide by the code of professional ethics and take every precaution to ensure that, above everything, PRIMUM NON NOCERE (“first, do no harm”).
Live Cell Therapy – Benefits And Side Effects
Live Cell Therapy is a surgical procedure, but is not a ‘magic bullet’. The principle of treatment must be holistic, and cell therapy is an integral part of it. The aim of treatment is not just to eliminate symptoms but to restore / revitalize the vital elementary functions of the body. Hence, the protocol of cell therapy must always incorporate a preparatory phase aimed at achieving the best physiological state possible for the patient.
Attention to detail to achieve an optimal internal milieu -or what cell therapists term as ‘the mesenchymal environment’– is important for good therapeutic effect.
It is believed that the benefit of live cell therapy is :
70% due to the direct stimulation of regeneration, and
30% due to transplantation of new cells
The probability of success will be enhanced if the patients for therapy are carefully selected, properly prepared, and the treatment carried out in accordance to the up-to-date protocol established by the experts in the field. So, if a patient wants to have this treatment, he needs to be fully informed and to follow the prescribed protocol to enhance the probability of success. Live cell therapy must always be an integral part of holistic treatment. If properly carried out and the patient adheres to the protocol, the benefits will be felt.
It is to be expected that not every patient receiving live cell therapy will admit to feeling the benefit of the treatment, particularly if the pre-treatment preparatory protocol is not adhered to. Even if no benefit is felt, side effects are infrequent. It is imperative that doctors performing cell therapy carefully screen patients for cell therapy, follow the protocol of treatment, and ensure that the live stem cells are procured from an accredited laboratory.
Patients undergoing therapy must be given full information as o the do’s and don’ts to enhance the effect of therapy. Expectations of benefits should be discussed between the doctor and the patients or parents. Like all models of medical therapy, no guarantee can be given that all the expectations will be realized. But the patients can be told that the therapy is safe; allergic reactions are uncommon, and side effects such as fever, rash, feeling of lethargy, and swelling at the site of implantation occur only very occasionally.
This is based on our experience of more than eight hundred implantations carried at Villa Medica.
Related Article – Case Studies: Cell Therapy – A Retrospective Study 2017
> Read the full article here
A Strong Mental Defence Mechanism
Live Cell Therapy is a part of a holistic treatment. This implies attention to the diet, hygiene, nutrition, proper rest and adequate exercise, and abstinence from alcohol, drugs, and smoking. Those with stress, depression, etc., may need a referral to a mental health professional to help them achieve psychospiritual balance.
Cultivation of a strong mental defence mechanism to be able to handle stress should be included in the aims of treatment. Patients have to cultivate patience, thankfulness, asking forgiveness, always with a sense of being in God’s grace, and a positive attitude.
For instance, a paraplegic having cell therapy should be prepared to undergo physical therapy. As a fellow cell therapist who had the same experience said,
You must strive with blood, sweat, and tears.
Receiving Cell Therapy but not being prepared to commit to an intensive physical therapy program and to struggle with patience and hope will be a loss. Cell Therapy has and will always be an integral part of a holistic approach to treating any patient with a chronic or untreatable disease in conventional medicine.
This article was peer reviewed by Dr. Burkhard Aschhoff.
“I must thank to Dato’ Seri Prof. Mike Chan and Dato’ Seri Prof. Michelle Wong, chairman of Fetal Cell Technologies International (FCTI), for their continuous and unwavering support. Their generosity in sharing their professional and technical knowledge and the vast experience they have garnered over these past twenty-five years in cell therapy research illustrate their trust, dedication, and devotion in sharing their unique and proprietary know-how to me.” – Dr. Abdul Halim
Meet the author
Dr. Abdul Halim bin Abdul Jalil
Pediatrician, Scientist, Stem Cell Transplantologist
Senior Medical Team Member of FCTI Asia Hub for Stem Cells.
More Details >
About the Publication
Hope for Untreatable Medical Disorders with Live Cell Therapy
A book by Dr Abdul Halim Abdul Jalil
Published by Matador, Troubador.co.uk, London – Medical Research: ISBN 978 1785898 969
Deposited with the British Library and lending libraries
Buy Online >
Further Reading – Quality Articles About Cell Therapy
- Niehans, P. Introduction to Cell Therapy. Pageant Books, Inc, New York, 1960.
- Lipton, B. The Biology of Belief. Hay House Inc., 2005.
- Schmid, F., Stein, J. Cell Research and Cell Therapy, Ott Publishers, Thun, Switzerland, 1967.
- Molnar, E. M. Textbook of Stem Cell Transplantation. Medical and Engineering Publishers, 2006.
- InSoo Kim, D.D.S., Ph.D. A brief overview of cell therapy and its product. Published online 2013 Oct 22.
- Gage FH. Cell therapy. Nature. 1998;392(6679 Suppl):18–24
- Nathalie Hirt-Burri, Albert-Adrien Ramelet, Wassim Raffoul, Anthony de Buys Roessingh, Corinne Scaletta, Dominique Pioletti, Lee Ann Applegate. Biologicals and Fetal Cell Therapy for Wound and Scar Management ISRN Dermatol. 2011; 2011: 549870. Published online 2011 May 18. doi: 10.5402/2011/549870
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